The Detroit Tigers announced their 2012 schedule on Wednesday, and will open the season at home on April 5 against the Boston Red Sox, as part of a six-game homestand against the BoSox and the Tampa Bay Rays.

Other notable home series include: The New York Yankees twice (June 1-3 and Aug. 6-9) and a four-game set against the Los Angeles Angels (July 16-19), which — barring a postseason meeting this season — will be the rematch from this year's contentious showdown between aces Jered Weaver and Justin Verlander. The Angels return to Comerica on Aug. 24-26, and the Tigers go to Anaheim on Sept. 7-9.

Interleague series include a home-and-home set with the Pittsburgh Pirates (May 18-20 at Comerica, June 22-24 at PNC Park), a home set against the Colorado Rockies (June 15-17) and a three-game matchup between good managerial friends Jim Leyland and Tony La Russa when the St. Louis Cardinals visit (June 19-21).

Key road series include two trips to Boston (May 28-31 and July 30-Aug. 1), a pair of National League Central visits to the Reds (June 8-10) and the Cubs (June 12-14).

Here's the full 2012 schedule on the Tigers' website.